Replies to post #22765 on Innovation Pharmaceuticals Inc (IPIX)

[kris_kade]

You are correct. Kevetrin should be effective (if the mouse models are accurate predictors!) in about 50% of cancers.

My interpretation is 50% of human beings and not 50% of cancers...the reason is as posted earlier, only 50% of human beings carry that mutant P53 gene

[a1derfullife]

The quote I published talked about extrapolating from observed effectiveness in pre-clinical (ie, mouse) models to phase 2 clinical results. If you go to CTIX's website and read through their presentations, you will observe that Kevetrin was shown to be active in 100% of the mouse models they tried. The quote indicated a ~ 50% likelihood of positive phase 2 results if a cancer drug showed positive activity in at least 33% of mouse cancer models. So, since Kevetrin showed significant activity (ie, effectiveness) in 100% of the mouse models, my conclusion is that the likelihood of Kevetrin being successful in phase 2 trials is substantially greater than 50%.

A1