Well said - Big Pharma is undoubtedly here. Big Pharma will want a huge stake in MANF and rest assured, with insider buying in the open market, IMHO something is definitely brewing here. The mere fact that Dr. John Commissiong was former director of the NIH alludes to his name recognition and deep rooted connections within the health field. Having Amgen and Bayer Squib CEO's on AMBS BOA's is unprecedented for a penny stock soon to become a dollar play in FY-13.