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Sirona's skin lightening compounds are safe, says study
2013-01-07 09:11 ET - News Release
Mr. Neil Belenkie reports
SIRONA BIOCHEM'S COSMETIC SKIN LIGHTENING COMPOUNDS PROVEN TO BE SAFE IN INDUSTRY STANDARD SAFETY STUDY
Sirona Biochem Corp.'s skin lightening compounds, TFC-849 and TFC-723, were proven to be non-genotoxic in an industry-standard genotoxicity study. The study, financed through a $1.9-million French grant, is led by TFChem and involves a consortium of partners.
In the study, the genotoxicity activity of compounds TFC-849 and TFC-723 was evaluated at a concentration range of nil to 5 per cent using a standard bacterial colorimetric assay. The SOS response to DNA-damaging (deoxyribonucleic acid) agents was measured to determine genotoxicity. Both depigmenting agents, TFC-849 and TFC-723, were proven to be non-genotoxic in the concentration range studied. "The genotoxicity results demonstrate further evidence of the strong safety profile of our skin lightening compounds, TFC-849 and TFC-723," said Neil Belenkie, chief executive officer of Sirona Biochem. "In scientific studies, our compounds demonstrated superior effectiveness and safety over the world's leading commercial skin lighteners. We believe we have developed skin lightening compounds that are both safe and effective, meeting an unmet demand for the multibillion-dollar skin lightening marketplace," he added. Genotoxicity testing measures DNA degradation, which can be evidence of potential mutagenicity or carcinogenicity.
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