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ghmm

12/03/12 3:39 PM

#153452 RE: genisi #153450

I thought they were going to treat for longer duration too. I thought Ligand had said years (in the plural) at a prior R&D day. They have their R&D day tomorrow I suspect it will at least get a passing mention but they usually don't give more details then their partners do.

masterlongevity

12/03/12 4:55 PM

#153455 RE: genisi #153450

i knew they were doing a ph2/3, but was very surprised to see this in mild to moderate AD. I had heard that this trial would be in MCI due to AD.

My estimate is that it will take them 6 months to enroll 200 subjects. I would bet they will take this from a ph 2 to ph 3 after they have 1 yr of safety and Biomarker data on ~100 patients. so maybe a switch to phase 3 within 1.5 years from now.

DewDiligence

03/13/13 8:40 AM

#158221 RE: genisi #153450

MRK partners with LMNX to develop companion diagnostic for BACE inhibitor, MK-8931 for AD:

http://finance.yahoo.com/news/merck-luminex-corporation-enter-agreement-123000042.html

No financial terms disclosed.