I would be more concerned with volume coming in all of a sudden than bid size changing. I have seen bid and ask sizes jump all over the place on stocks that have no activity. If you see some prints coming through all of a sudden, you might have a slight chance of activity and an uptick. Triple zero stocks with bids of .0001 that stop trading are tough. Only scenario worse that I can think of is one with a .0001 ask and no bid.
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