Not offended...
Twice, and immunbiologic text books. It's a bad attempt at being condescending to me for what I've all ready been learned. That's okay.
Since I've lost you, and it's my fault, for my inability to convey the subject. That's were I've failed.
Immunogenetics would be where I'm losing you, I think?, and the genetic variations that Bavituximab immunological targeting pathway (scientific worm hole) to influence disease outcomes? Yes, and if so, then, without being condescending myself, please consider yourself for reading.
RE: V(D)J recombination
Its the process of V(D)J recombination and Cytokines that are responsible for class switching. You know? B cells of the immune system perform genetic recombination, called immunoglobulin class switching. It is a biological mechanism that changes an antibody from one class to another, for example, from an isotype called IgM to an isotype called IgG
So, you ask whats this have to do Bavituximab? Bavituximab can only do effect in tumor angiogenesis, and tumor vasculature? Yes, and king of immunity food chain, I say.
Finally, if I come across as arrogant, it's not intended, but mistaken for confidence maybe? FTM, when I get the right brush to paint you a picture, I surely will, and please have patience with that.
Lastly, do you object to me saying, "an increase in Nitric Oxide, and a decrease in ATP, are the chemical signaling Peregrine was referring to in last PR? If so, I can at least eventually get us to my theory, and if not we will seize any future communication, or prove me corrected. Thanks.
All above is my opinion,
John