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vinmantoo

09/13/12 2:07 AM

#148767 RE: jq1234 #148751

{{Do you know if they had ever collected RAS status in any trial including this one to test the hypothesis? It doesn't seem they have to me.}}

jq1234,

I don't if ONCY tested the RAS status, but given the ability of Reolysin to replicate in RAS activated cells selectively, it seemed to me to be a no brainer to assay the primary tumor. I have been out of ONCY for about 5 or 6 years and I recall one of the frustrating things for me when I owned ONCY was management seemed to lack the urgency and the wisdom to make RAS testing a priority.