Replies to post #148283 on Biotech Values

[mcbio]

Is Roche's RG7421 the partnered drug with EXEL? I dont know if it EXEL's drug after all. On their site, it says RG7421 is partnered with EXEL, but I saw a brochure they made from 2012 that says differently(lists GDC-0623 as the other name for RG7421). Very confusing.

I believe the answer is yes given prior discussion around the EXEL MEK (#msg-71247547 ). 'RG' is just Roche designation whereas 'GDC' is a Genentech abbreviation I believe.

[jq1234]

I have complained for quite some time now that the goal of Roche's RG, RO, and GDC naming system is to confuse anyone to actualy look at their pipeline.

Just do a search on XL518, you'll come up with equivalent of GDC0973/RG7421 all over the internet. Here is the MEK/BRAF combo trial:

http://clinicaltrials.gov/ct2/show/NCT01271803?term=GDC-0973&rank=3

Here is the MEK/PI3K combo trial:

http://clinicaltrials.gov/ct2/show/NCT00996892?term=GDC-0973&rank=4