Various Big Pharma CC’s from the past few years—I can dig up excerpts (or you can) if you’re interested.
The issue is not that warfarin patients in Europe have been shifted en masse to the new oral anticoagulants, but rather that warfarin was not heavily used in Europe in the first place, despite its being the quasi-official SoC for certain indications.
Anticoagulation guidelines should be updated soon (probably early next year), the novel anticoagulants will be reflected and their use should be boosted.
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