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entdoc

08/22/12 9:50 PM

#88159 RE: asmarterwookie #88158

wook, heavy: You wrote, "Data presented yesterday(1) at AACR demonstrated that a near infrared-labeled PS-targeting imaging agent (NIR-PGN650) was able to specifically identify and target multiple solid tumors. Data also showed that NIR-PGN650 could demonstrate a measurable increase in PS exposure in tumors following chemotherapy."
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Bungler

08/22/12 10:52 PM

#88167 RE: asmarterwookie #88158

Yes, that is what I thought . . . the mab has to be image agent-labeled. That is why the post about the second arm being "cut off" threw me. I thought Bavi had only two "arms." One to dock to the PS and the other to either carry a payload, call in the macrophages, or to carry the imaging agent. If the other arm has to be "cut off" then to what is the NIR label attached?