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vinmantoo

08/20/12 11:38 AM

#147403 RE: porkchop11 #147398

porkchop,

I think I make it quite clear and the wiki article supports what I stated. Apoptosis is programmed cell death. During embryogenesis, healthy cells are induced to die to enable structural changes. A notable final stage failure of apoptosis is manifested is the disease syndactly, where people have webs between their fingers and toes excuse the healthy tissue between the digits failed to undergo apoptosis. There are other situations where apoptosis comes into play, such as when cells receive mixed growth signals or poorly execute a process, such as when they undergo a catastrophic mitosis and stall then undergo apoptosis as a defense against aneuploidy. Nobody would call apoptosis "normal" cell death.

Necrosis is more of what one would consider "normal" cell death, where accumulated damages result in death.