When a company has NOTHING left, like ASYI, and there is no other source of income, like ASYI, the only way to survive is selling stock. A reverse split is a artificial way to raise the price in a effort to create the illusion of a company with some value. It catches some people off guard when they fall for the usual "merger, big news coming" kind of rhetoric. R/S, sell, R/S, sell, wash, rinse, repeat.
Legitimate companies may reverse split to get the price up into a range more suitable to entice funds to buy because funds generally have a low limit for what they allow themselves to invest in.
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In answer to your reply: A run is dependent on many things. News? Promo? Organized false momentum? ASYI with no news, vague speculation, baseless ideas probably wouldn't run far if any at all. Get a REAL bit of good news and it could go up but how high depends on what and how good the news is. Right now there is nothing to justify a run. IMO