Entdoc, the new phase I trial in stage 2 & 3 rectal cancer before surgery might answer some of your questions. I do think bavi would have more success with smaller tumors. Seeing how the MOS for the second-line NSCLC treatment arms have not yet been triggered I would say that bavi works fine in stage 4 cancer, which is quite amazing.
First let me say that as a non science guy it is a privilege to read the ongoing debate. The education and reading material on this board are an added bonus when investing in PPHM. A layman like me should pay a fee for the entertainment and education from this board.
As an uneducated observer my take would be that an early stage patient would have the added benefit with Bavi catching the cancer cells that escape the primary tumor and enter the blood stream attemptinh to metastasize into other areas of the body.
As we all know it isn't always the primary cancer site that kills you.
Sally Ride succumbs to pancreatic at 61 cancer RIP.
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