Replies to post #84628 on Avid Bioservices Inc (CDMO)

[Robert C Jonson]

Thanks for sharing, RRDog, very nice report!

[PGG76109]

RRdog great post thank you for taking your time to post that

[entdoc]

rrdog, agree, listening to Thorpe's NYU talk once or twice should be routine DD, but a slow sled for non-scientists. It's great that his thinking has your (and my) endorsement as "the real deal". I continue to be a bit surprised by Thorpe's answer, "they are all pretty sick", when asked which patient subset benefited more from Bavi. IMO huge value resides in increased efficacy in less ill patients. Stated in the opposite, it is known that many of the most severely ill patients in clinical trials have immune systems that are in advanced states of collapse. I suppose the answer is, "we haven't been given the chance to try it in less ill patients." I hope that day comes soon.

[freethemice]

RRdog, after listening a few times I was surprised that the first time I had missed the stuff about exosomes.
At least one of the missing slides was about exosomes. Thorpe does talk about PS on exosomes and how
blocking that is another way to reduce immunosuppression. I am looking forward to the paper on
awakening the immune system with bavi that must be on the way. Is there a way I can send you something?