Replies to post #81255 on Avid Bioservices Inc (CDMO)

[freethemice]

RRdog, sorry not to answer before but I was on vacation. In all these studies I only report what the paper stated.
The results are better, but not statistically significant, as reported. It is all in how things are calculated and the
spread of the data. The noise in the data plays a part here. The medians may look different but if there is a lot
of variability present the medians can't be statistically distinguished. That can explain the difference from
one trial to the next. That is how I interpret it.
From the paper:
D + C (N = 67), D (N = 65)
Median survival (months) 10.27 7.70 P = 0.550 (Log-Rank test)
Min - Max 0.7 - 36.8 0.5 - 43.2
95% CI (7.07 - 13.47) (3.39 - 12.01)

The 95% confidence limits for docetaxel almost totally overlap the 95% confidence limits for docetaxel + carboplatin