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DewDiligence

05/28/12 9:22 PM

#142797 RE: jq1234 #142791

GSK combo maybe will show how two average TKIs combined together can produce more dramatic result than each on its own.

It’s notable that this has rarely if ever worked with combinations of mAbs.

genisi

05/29/12 5:46 AM

#142805 RE: jq1234 #142791

GSK will present dabrafenib monotherapy in ph3 melanoma result at ASCO as well. Would be interesting to see efficacy relative to Zelboraf. If I remember correctly the earlier efficacy result wasn't as striking as Zelboraf.

Thanks for the pointer, I've skipped it as the abs. isn't available yet. I don't think GSK ever presented PFS and OS data from phase II, so are you talking about phase I data?