That’s the $64,000 question. EXAS has done a lot of work in this regard and is still doing more (to potentially upgrade the assays) concurrently with running the DEEP-C study—see http://www.clinicaltrials.gov/ct2/show/NCT01260168.
All told, EXAS’ ColoGuard is a fairly high-risk program, IMO; however, there’s a very compelling medical need for something better, more tolerable, and less invasive than standard or virtual colonoscopy (even with the no-prep software enhancements). GIVN’s PillCam COLON 2 could play a role in this market, but it hardly seems like the ultimate solution.