fTm, now you're cookin'(as usual). You're usually so "right on" that an occasional flight of fancy is to be human. Agreed there is probably a wide variation in representation of flipped -PS on tumor vasculature, and there might not only be a variation in that phenom. between mice and man, but there also might be a place for "pre-sorting" Bavi treatment "candidates" (if we can get this goose off the ground). Good thought. I believe Thorpe,et.al., have always used the modifier "most" when referencing solid tumor types. all imo