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mojojojo

04/16/12 3:03 PM

#78703 RE: entdoc #78702

From the 4/3/2012 PR.

“We are very excited by the diagnostic imaging potential of our proprietary PS-targeting technology platform and feel that this addition to our clinical pipeline could hold considerable value. Molecular imaging agents represent a large and rapidly growing market. With improved personalized oncology therapies becoming a reality in recent years, there is a growing need for products that can quickly assess a patient's response to therapy and PGN650 has shown considerable promise in this area. Our initial goal for the PGN650 program is to further validate the broad nature of the PS-targeting platform. Results from this study may open the door for multiple applications including antibody drug conjugates (ADC), the ability of 124I-PGN650 to monitor the effectiveness of current standard cancer treatments, and the ability to potentially select patients that may do better in bavituximab based treatment regimens."

freethemice

04/16/12 3:38 PM

#78711 RE: entdoc #78702

Entdoc, I am just saying that all that we know is from mice/rat studies, have we
ever seen imaging of human tissues showing that PS is exposed on the tumor vasculature?
I am with you that I find it hard to believe that it wouldn't be there, but it would be nice to
confirm it. Also, to confirm that it is on all the tumors.