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JJM760

03/22/12 11:18 AM

#17501 RE: DonShimoda #17500

I asked Berger about that at a conference in NYC. He pretty much indicated the market was not juicy enough for Mrk to move forward.

BTH

03/22/12 12:46 PM

#17504 RE: DonShimoda #17500

They have some trials going on with MK-2206 (Akt) that will probably do well. Akt is somewhere along the PI3K

http://clinicaltrials.gov/ct2/show/NCT01295632

I think going forward these will probably bear some fruit - but - not before Ariad probably has a lot more data on '113 so all this will be relatively meaningless in the scope of things.

I never really liked ridaforolimus. The combo trials will be were it shows its true efficacy.