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nivasvs

02/18/12 4:42 PM

#137345 RE: mcbio #137339

"Any comments on a glucokinase activator for T2D?"

I don't have any comment specific to GKA.

However, my biggest concern with drugs that target liver is safety issues, such as elevated liver enzymes. I have seen same problem with GCGR, however, excellent glucose lowering was.