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surf1944

03/08/12 4:10 PM

#156 RE: surf1944 #141

3:23PM Sangamo BioSci presents new clinical data demonstrating persistent positive effects of ZFN Therapeutic for 'Functional Cure' of HIV/AIDS (SGMO) 5.13 +0.17 : Co says "The results suggest that SB-728-T has a positive effect on immune health of HIV-infected patients and this effect is persistent for over a year in some subjects. Most importantly, SB-728-T treatment provides HIV-resistant T-cells that are capable of mounting an immune response to an inflammatory event in lymphoid tissues and has yielded encouraging effects on HIV viral load when antiretroviral drugs are withdrawn during a treatment interruption... These data add to our understanding of the positive viral load changes in SB-728-T-treated subjects, and suggest that an early cytokine burst may initiate the dramatic and prolonged increase in CD4 counts observed following SB-728-T treatment."