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biomanbaba

01/30/12 10:37 AM

#381 RE: kris_kade #380

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biomanbaba

01/30/12 10:43 AM

#382 RE: kris_kade #380

these remarks support my thesis that cancer will be cured in THIS decade...and will be a cocktail of already known therapeutic agents PLUS things like T302 and the compounds your referenced article describes
...thank you for posting

"With several known mechanisms by which cancer recurrence is enabled, scientists are discovering that recurrence can be additionally driven by a small population of cells in tumors known as cancer stem cells (CSCs) or tumor initiating cells. Conventional cancer treatments, such as radiotherapy and chemotherapy can kill normal tumor cells that grow quickly and as a result are more susceptible to these agents. These standard of care treatments, however, are unable to eliminate CSCs as these cells grow more slowly and more closely resemble healthy cells in their resistances. As a result, the tumor(s) can eventually return due to these remaining CSCs with an apparent increased resistance (one might even say "learned") to the agents used to kill the first generation cancer cells. Pertaining to CSCs and other mechanisms driving cancer recurrence, Professor of Oncology, Hyram Levitsky, of John Hopkins University stated:

"Well over 50% of the common cancers can be treated into a state of minimal residual disease. What we lose patients to is typically not the inability to get the disease into that minimal state, but rather the inability to completely eradicate the residual component. "