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genisi

01/18/12 12:42 PM

#135284 RE: NP1986 #135278

We're on the same wavelength about regorafenib clinical relevance #msg-71008932

vinmantoo

01/18/12 1:07 PM

#135288 RE: NP1986 #135278

Overall survival is the metric that won approval for Nexavar in HCC, not PFS. Regorafenib appears to be following that pattern, so I think the focus on the small but not statistically significant increase in PFS for Regorafenib is misplaced.

DewDiligence

05/09/12 1:57 PM

#141654 RE: NP1986 #135278

Erbitux fails to improve DFS when added to chemo in adjuvant (post-surgical) CRC:

http://in.reuters.com/article/2012/05/09/us-merck-idINBRE8480C820120509