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Tamhas

01/15/12 12:58 PM

#135093 RE: genisi #135092

Color blindness and haemophilia are two very common Y linked disorders. Try googling on Y linked disorder for many.

ghmm

01/15/12 1:21 PM

#135094 RE: genisi #135092

I'd probably fail the quiz but I get your point (I think).

I recall TKT saying they believe the incidence of females was likely to equal that of males. I don't recall if there was any data on the severity of the disease or the age of onset of symptoms.

turtlepower

01/15/12 1:33 PM

#135095 RE: genisi #135092

Well i'll give it a stab.

Females could have one healthy x chromosome and therefore the alpha-gal enzyme levels could be close to normal levels. Males on the other hand will have little to no alpha-gal because the only x they have will be mutated. Therefore the alpha-gal activity increase can be better observed in males because they will have little to begin with.