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12/19/11 7:46 PM

#133370 RE: DonShimoda #133365

I really think companies should develop their drugs in a way that would allow them to by-pass a lengthy Phase 3 trial, similar to what Ariad is doing with Ponatinib. Clearly Pona is a unique example. Problem is, a lot of development companies are borderline scams that are just ATM machines for Executives and Board Members so their Phase 1 trials are complete nonsense, instead of a true Phase 1/2.

I read a really good abstract not too long ago re: avoiding Phase 3 trials by designing better focused trials based on personaized medicine. ...which would hopefully speed up the nonsense of taking 15 years to get a drug from lab to marketing approval.