Replies to post #121 on Sangamo Biosciences Inc (SGMO)

[Teedlum]

I think Motley Fool got it right:

"The patient who has been essentially cured of HIV already had one non-functional copy of CCR5. By knocking out the functional copy, the cells were left with no CCR5 genes.

To make this work beyond the 5% to 10% of HIV patients with a genetic mutation in one copy of CCR5, Sangamo needs to figure out a way to delete both copies of the gene in the T-cells."