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NP1986

09/26/11 9:34 AM

#12863 RE: micanwait #12852

If approved as a front line therapy, what would be the size of the market?



The front line market potential is >$2 billion and growing. The problem is ponatinib would be facing competition against second generation agents like Tasigna and Sprycel, and against Gleevec which would be available as a generic by the time Ariad completes a head-to-head phase III trial.