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oc631

09/01/11 8:30 AM

#140 RE: hptaxis #139

Welcome aboard.

I'm focused on the efficacy of PSI-7977/SOC in GT2/GT3 patients going into AASLD this November. The company continues to shorten the treatment duration (with one cohort down to 8 weeks) in what the CEO calls a game of limbo. At some point the drug combo will lose the 100% efficacy seen at 12 weeks but if all patients in the 8 week cohort achieve SVR's it would be unprecedented and the FDA may be willing to bring the drug to market early for the underserved GT2/GT3 market. There seems to be no safety or tolerability issues with this drug.

If this occurs even the most bullish analyst estimates may fall short next year.