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genisi

06/15/11 2:08 AM

#121668 RE: jq1234 #121628

I'd say Alpharadin is an anti-cancer drug.

A matter of definition. I can argue that it's a bone oriented therapy with anti cancer activity, so the more accurate title would be an "anti bone metastases" drug :
"About Alpharadin...This compound mimics many of the behaviors of calcium in the bone." (http://www.bayer.com/en/news-detail.aspx?newsid=14775).
Anyway, my point was about a bone targeted therapy in cancer that can benefit OS.

Xgreva is different.

Agree. Still, Xgreva inhibits bone turnover so it's a pure "bone" drug by it's mechanism, but it can impact OS in CRPC patients, which makes it an "anti cancer" therapy as well.