Do you think it's possible they anticipate a combo strategy of an m-tor with another med may work better, and it's keeping them from commiting to a single drug trial, despite the great pII results.
Could it be that they think a multi target strategy(like Cris's) is more viable?
Don't know if anyone has such a trial(another m-tor plus something else, or a multitarget single drug)in the hopper for endo.