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DewDiligence

04/26/11 2:29 PM

#118872 RE: pcrutch #118866

This might be a good time for VRTX longs to take some chips off the table. The enterprise value now exceeds $10B.

Telaprevir will clearly be a big-selling drug, but for how long? The rate of new HCV infections is small, so there will be fewer patients to be treated in 5-10 years than there are today.

Moreover, newer and better HCV protease inhibitors are coming that will, in all likelihood, supplant the first-generation PI's within a few years (#msg-62384804).

Despite scientific success in CF, VRTX is essentially a one-trick pony. For all practical purposes, it’s a short-lived trust fund for Telaprevir profits.

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ghmm

04/26/11 2:37 PM

#118875 RE: pcrutch #118866

I didn't look at the docks and since I have no vested interest probably won't. Curious if anyone has looked at them in detail if there was anything more about the rash then the company let on? I am guessing nothing of substance based on the price movement. I had suspected VRTX of trying to downplay the rash and it being more burdensome especially when the drug would be used outside of a clinical trial setting where it could be observed/managed better. I would wait for the Adam F. Readers digest version but up till the past year or so he had been quite biased in their favor.