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oc631

04/04/11 10:07 AM

#117538 RE: genisi #117537

EASL - first SVR data for mericitabine (a.k.a RG7128 ) interim analysis from the Jump-C phase 2b study. Note the high relapse rate





Surprising to see such a high rate in combination with SOC. Do you think Roche will move forward with the PROPEL study? How about INFORM? I am obviously biased towards the nuke class but to me Jump-C just argues for VRUS' strategy going forward.

dewophile

04/04/11 1:27 PM

#117553 RE: genisi #117537

the next generation nukes from VRUS look to be better - and 3 AA substitutions were necessary for development of resistance for at least one of the follow on nukes (not sure about RG7128 resistance)

DewDiligence

04/04/11 3:21 PM

#117564 RE: genisi #117537

What’s the over/under on the number of days until Roche officially dumps this drug? It makes no sense to continue development, IMO.