CannabidiolFrom Wikipedia, the free encyclopediaJump to: navigation, search
Cannabidiol
Systematic (IUPAC) name
2-[(1R,6R)-6-isopropenyl-3-methylcyclohex-2-en-1-yl]-5-pentylbenzene-1,3-diol
Identifiers
CAS number 13956-29-1
ATC code noentry
PubChem CID 644019
DrugBank none
ChemSpider 24593618 Y
ChEMBL CHEMBL190461 N
Chemical data
Formula C21H30O2
Mol. mass 314.46
SMILES eMolecules & PubChem
InChI[show]InChI=1S/C21H30O2/c1-5-6-7-8-16-12-19(22)21(20(23)13-16)18-11-15(4)9-10-17(18)14(2)3/h9,12-13,17-18,22-23H,2,5-8,10-11H2,1,3-4H3/t17-,18+/m0/s1 Y
Key: ZTGXAWYVTLUPDT-ZWKOTPCHSA-N Y
Physical data
Melt. point 66 °C (151 °F)
Boiling point 180 °C (356 °F)
(Range: 160°C-180°C) [1]
Therapeutic considerations
Pregnancy cat. ?
Legal status Schedule II (Can)
Unscheduled (USA)
N(what is this?) (verify)
Not to be confused with Cannabinol, a separate cannabinoid.
Cannabidiol (CBD; pronounced /?kæn?b?'da?.?l/) is a cannabinoid found in Cannabis. It is a major constituent of the plant, representing up to 40% in its extracts.[2]
It has displayed sedative effects in animal tests.[3] Some research, however, indicates that CBD can increase alertness.[4] It may decrease the rate of clearance of tetrahydrocannabinol (THC) from the body, perhaps by interfering with the metabolism of THC in the liver.
Medically, it has been shown to relieve convulsion, inflammation, anxiety, and nausea, as well as inhibit cancer cell growth.[5] Recent studies have shown cannabidiol to be as effective as atypical antipsychotics in treating schizophrenia.[6] Studies have also shown that it may relieve symptoms of dystonia.[7][8]
In November 2007, it was reported that CBD reduces growth of aggressive human breast cancer cells in vitro and reduces their invasiveness.