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vinmantoo

01/31/11 2:24 PM

#113734 RE: genisi #113716

<It's true that BRCA mutations represent a very small subset (and very resistant btw) of patients with breast cancer but various other cancers are linked to these mutation.>

Quite right, but if you are designing a therapeutic regimen it might be better to have a high percentage in a few defined cancer types, rather than a very low percentage occurence in a variety of cancers. Well, you could do genetic screening to parse out the BRCA mutations.