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gpo344

12/22/10 8:09 PM

#4321 RE: DonShimoda #4320

So no doubt Ponatinib will be used for the T315 mutation, but is that enough of a monetary return that it would cause Ariad to be worth the numbers that are being thrown around? Are there other indications that would propel it to the top of the list?
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biotech_researcher

12/22/10 8:11 PM

#4322 RE: DonShimoda #4320

IMHO, even more important, is that preliminary phase I results indicate, that Pona can arrest/block the T315I mutation from mutating in the first place. In other words, with Pona, you lessen the chance in developing the T315I mutation. Read that information in the last Pona update. That will certainly cause Pona to move to the first level of treatment for certain CML patients. Some doctors will provide their patients the Lexus treatment..