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DewDiligence

12/06/10 3:43 PM

#110202 RE: DonShimoda #110200

ARIA—The geographical differences in first-line risk classification presumably stem from differences in the the stage of disease (chronic, accelerated, or blast) when diagnosis is made.

biomaven0

12/06/10 5:25 PM

#110211 RE: DonShimoda #110200

strategy of keeping the US rights and partnering what could arguably be a much larger opportunity



But in dollar terms the difference is not nearly as great - the countries with more high risk patients (presumably, as Dew commented, because of later diagnosis or poor initial treatment) are also likely the ones that can't afford to pay much.

Peter

DewDiligence

06/08/11 3:18 PM

#121280 RE: DonShimoda #110200

NCCN just updated its treatment guidelines for CML; the update is in this 64-page document:

http://www.nccn.com/images/patient-guidelines/pdf/cml.pdf

I do not know what the changes are.