Thanks for checking. I've been thinking the same thing though I too didn't want to get excited for the same reasons.
I was originally content to wait until December for the updates but I am very hopeful that they do it within the next two weeks. My Christmas list is still the same though:
1) validation study results of the urine test:
-"The Company expects to be eligible for the milestone payment by year-end."
That indicates the end of P2 and the completion of the urine study. Based on the results, Abbott would continue with P3 and pick up the costs for the test kits. Quest and Abbott would also continue with the LDT for the urine test as there would be official confirmation that the urine test works. (They would not have tried to market the LDT based on tissue test results from the prior, published study. Besides detecting cancerous cells, if the 4-gene test can distinguish BPH as well as they think, the urine test may only be the beginning:
-"This same set of genes also separated BPH from normal tissue patterns, indicating that BPH is a disease with molecular characteristics of its own. This discovery could be used to develop a new non-invasive diagnostic test for BPH, which does not currently exist, as well as a completely new type of therapy for patients with this disease. This patent-protected gene set was developed in association with an international pharmaceutical company to be used as a surrogate biomarker for their clinical trial evaluating a new BPH drug."
2)The melanoma app:
On the change of tone from quarterly reports, it looks like they have gone on a slight tangent and is developing something just for dermatologists:
-"A beta version of the app for use in clinical settings has been completed and the Company is working on deployments with dermatologists for field testing."
Similar to MELA, if HDC has developed a strong algorithm, it only makes sense to continue and develop a non-invasive tool for dermatologists to diagnose cancerous from non-cancerous cells. Interestingly, MELA has developed a hand-held device for use in the clinic but their might be question as to whether they will receive approval from the FDA because the algorithm may not sufficiently achieve statistical significance.
That's not to say that they stopped working on the risk assessment tool for the general public.
-"A more advanced version of the app with features and a user interface optimized for consumer use is currently in development."
3) Other validity tests:
-"The Company hopes to complete validation of its test for leukemia in 2010."
Its completion would not only lead to another LDT, but also the confirmation that the flow cytometry interpretation product is effective and up for partnership/ sales. I also believe that other huge tests would be the pancreatic and breast cancer tests. I don't expect validation to be completed by next year but a early detection tests will save many lives.
With the increasingly successful use of SVM's in research studies all over the world, it cannot be denied that the method is useless. Though relatively new in its own development, SVM is making its impact felt in the science community. Even if HDC is only able to monetize a small fraction of their intellectual property, we'll all be financially secure. I don't necessarily agree with all of the company's policies or actions, but I believe they are in the right direction on the road to revenue. I only hope we will ALL look back at these times and just be thankful we saw HDC before its success and say "We were there."