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Heurtebise

10/09/10 3:06 PM

#8680 RE: tryn2makamil #8679

Thanks for checking. I've been thinking the same thing though I too didn't want to get excited for the same reasons.

I was originally content to wait until December for the updates but I am very hopeful that they do it within the next two weeks. My Christmas list is still the same though:

1) validation study results of the urine test:
-"The Company expects to be eligible for the milestone payment by year-end."
That indicates the end of P2 and the completion of the urine study. Based on the results, Abbott would continue with P3 and pick up the costs for the test kits. Quest and Abbott would also continue with the LDT for the urine test as there would be official confirmation that the urine test works. (They would not have tried to market the LDT based on tissue test results from the prior, published study. Besides detecting cancerous cells, if the 4-gene test can distinguish BPH as well as they think, the urine test may only be the beginning:
-"This same set of genes also separated BPH from normal tissue patterns, indicating that BPH is a disease with molecular characteristics of its own. This discovery could be used to develop a new non-invasive diagnostic test for BPH, which does not currently exist, as well as a completely new type of therapy for patients with this disease. This patent-protected gene set was developed in association with an international pharmaceutical company to be used as a surrogate biomarker for their clinical trial evaluating a new BPH drug."

2)The melanoma app:
On the change of tone from quarterly reports, it looks like they have gone on a slight tangent and is developing something just for dermatologists:
-"A beta version of the app for use in clinical settings has been completed and the Company is working on deployments with dermatologists for field testing."
Similar to MELA, if HDC has developed a strong algorithm, it only makes sense to continue and develop a non-invasive tool for dermatologists to diagnose cancerous from non-cancerous cells. Interestingly, MELA has developed a hand-held device for use in the clinic but their might be question as to whether they will receive approval from the FDA because the algorithm may not sufficiently achieve statistical significance.

That's not to say that they stopped working on the risk assessment tool for the general public.
-"A more advanced version of the app with features and a user interface optimized for consumer use is currently in development."

3) Other validity tests:
-"The Company hopes to complete validation of its test for leukemia in 2010."
Its completion would not only lead to another LDT, but also the confirmation that the flow cytometry interpretation product is effective and up for partnership/ sales. I also believe that other huge tests would be the pancreatic and breast cancer tests. I don't expect validation to be completed by next year but a early detection tests will save many lives.

With the increasingly successful use of SVM's in research studies all over the world, it cannot be denied that the method is useless. Though relatively new in its own development, SVM is making its impact felt in the science community. Even if HDC is only able to monetize a small fraction of their intellectual property, we'll all be financially secure. I don't necessarily agree with all of the company's policies or actions, but I believe they are in the right direction on the road to revenue. I only hope we will ALL look back at these times and just be thankful we saw HDC before its success and say "We were there."
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ou71764

10/09/10 3:50 PM

#8681 RE: tryn2makamil #8679

tryn

It's possible that it's significant. But there's the possibilty that it involves something between Quest and Abbott, and the timing of our shareholder mtg. is a coincidence. We'll find out soon enough!

But good points on Abbott being overdue. And if they want to build up the significance of the test, it would help to have a second party (Quest) announcing that it's a break through at the same time. If one corporation says it's going to be big, it could be perceived as self-serving...if two say it at the same time, it will get more media and investor attention.

Of course none of us are counting on it...but there's no reason to not stay optimitic and keep our fingers crossed. We all thought the prostate test(s) were going to be HUGE! If so, at some point someone is going to have to step forward and announce it to the world. Why not on a couple of pre-market PRs on the 20th! I will be watching for PRs from them! :)

ou
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Karlandang

10/09/10 5:57 PM

#8682 RE: tryn2makamil #8679

Hi Tyrn

For your sake I hope some great news is released very soon. I have not lost any faith. In fact, my faith is stronger than ever since Dr's Alibtar and Fritche have joined us. I don't know if you have the time, but I think you would feel much better if you did some thorough research on the backgrounds of these two recent additions. These are top notch big time individuals!!! They must see some great potential to join us. You know what they say, follow the money. I think these guys smell some serious money to be made here.

I have done a lot of dd on the technology. It works, it's being used in a plethora of research!! I use plethora for Ou. I thought he would like that.

As far as Abbott and Quest moving up their quarterly reports, I doubt they did that so they can make an announcement in regards to the prostate tests. I hope that I'm wrong.

I hope that your able to keep holding your HDVY shares. IMHO the companys IP is very likely to put us "on the map". I hope that they are staying on top of IP infringment. It appears to me they will have some cases coming down the line. I have no reason to believe they are not on top of this situation. I suspect they are waiting for the right time.

Best wishes

Karl
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rocketeer357

10/09/10 10:08 PM

#8687 RE: tryn2makamil #8679

You gotta believe!!! Thanks for the lift after my BMOD soiled the sheets last week. Especially appreciate those CAPS!!
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king oil

10/10/10 2:10 PM

#8688 RE: tryn2makamil #8679

Tryn, I hope you manage to hang onto most of your shares until the big payday (assuming it comes) after enduring for so long. I think there's a chance that the annual meeting is coordinated with those other dates because HDVY never has an annual meeting. So why this year? The only item on the docket is to elect the BOD, so I'm guessing if there's big news it will come right before or during the meeting (it would have to be PR'd or they couldn't tell people at the meeting). I hope Barnhill will at least explain what happened with Pfizer, what's going on with the melanoma app, why they didn't renew Tobin's contract but then gave him so much on his departure.