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zipjet

08/19/10 7:23 PM

#101954 RE: DewDiligence #101952

Robyn Karnauskas of Deutsche Bank forecasts that US Tysabri sales will fall from $633M in 2010 to $376M in 2015 as newer and safer MS drugs reach the market.



I'm all in for safer, IF EFFECTIVE, MS treatments. (My wife is on Tysabri after failing Copaxone.)

BUT what I am hearing is that Gilenia carries a cancer risk. Weighing a quantifiable PML risk against an unquantifiable cancer risk versus the ravages of MS is awful.

ij
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DewDiligence

10/26/10 8:04 AM

#107236 RE: DewDiligence #101952

Copaxone Continues Cleaning Tysabri’s Clock in US Market

[Updated for 3Q10 Tysabri sales.]


The US market is the one of consequence for MNTA investors insofar as
this is where MNTA/NVS have submitted an ANDA for generic Copaxone.
Below are Tysabri and Copaxone US sales for the past nine quarters with
the recent year-over-year and quarter-over-quarter growth rates. Copaxone
outsells Tysabri in the US by better than 3:1.


-------TYSABRI------- ------COPAXONE-------
US $M Y-o-Y Q-o-Q US $M Y-o-Y Q-o-Q
Sales Change Change Sales Change Change
3Q10 151 +15% +4% * * *
2Q10 145 +16% +7% 531 +21% +4%

1Q10 135 513
4Q09 137 509
3Q09 131 540
2Q09 125 438
1Q09 116 430
4Q08 115 384
3Q08 122 352

*Teva reports 3Q10 Copaxone sales on Nov 2.