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DewDiligence

08/03/10 12:21 PM

#100529 RE: genisi #100528

The prevalence of the EML4-ALK fusion oncogene is higher among lung adenocarcinomas, in non or light smokers, and in EGFR, KRAS-negative cases.

Are there significant commercial ramifications associated with this observation (apart from the raw frequency of the variant)? T.i.a.

poorgradstudent

08/04/10 8:53 AM

#100628 RE: genisi #100528

ARIA's ALK inhibitor is apparently slated for IND in mid-2011.

Pretty disappointing from my point of view.