I like this comment by Malcolm from the January 5, 2005
CytoGenix Scientists Discover Unique Gene Knock-Down Sequence to Kill Resistant Staph Bacteria ,PR
"We are at the point that by using our proprietary genomic techniques, we can screen for gene targets and develop effective compounds to inhibit disease causing activity in a matter of months rather than the years required for traditional drug discovery. For this reason we have been able to readily isolate several lead drug candidates against these resistant bacteria strains." adds, Dr. Skolnick
This means that time is quicker in knock down sequences,things are going to happen much faster now .IMHO