Replies to post #87741 on Short Term Traders-Listed Stocks

[clairmontasap]

working on a research proposal for those interested:

Quantification of mRNA in mice at various time intervals following Stroke episode to determine levels of Cytosolic phospholipase A2 alpha and Cyclooxygenase 2 as relates to the Arachidonic acid pathway of prostaglandins production and post-trauma inflammation

Background
Cytosolic phospholipase A2 alpha (cpla2 a) is an enzyme which generates production of arachidonic acid from phospholipid molecules by liberating the fatty acid from the phospholipid bilayer. Arachidonic acid is a precursor which through oxidative metabolism with the enzyme Cyclooxygenase 2 (COX 2) catalyzes production of the eicosanoids the prostaglandins; inflammation causing lipids.
The fact that cpla2 a is “essential for both the immediate and the delayed phases of eicosanoid generation” as Fujishima et al stated has not been contradicted and shows a direct link between the enzyme level and inflammatory response. The research showed that for both immediate prostaglandin production from arachidonic acid as well as delayed prostaglandin manufacture with activation-dependent induction of prostaglandin endoperoxide synthase 2 cpla2 a was necessary.