I'm shocked that noone else seems to be following this one!
I have a large position in ISIS and actually lightened up a little today as I've been having a lot of fun trading it too. The way it closed I'm a little concerned about getting back my full position at a good price. Sort of hoping for a market selloff tomorrow to give me a chance but today's strength was impressive. I saw that DNA money become available today which might explain overall biotech strength.