Well, if the economy is the in sh*t, people out of work and you have 2012 media job that's it's the end of the world then the two best plays would be shorting the market and finding a hot blond/brunet (that is otherwise out of your league) that really wants to get laid before the world comes to an end.
Who knows where this might lead. Lots of dead ends, but also probably some very interesting possibilities especially in a specialized society.
A friend brought up and interesting pt. They are finding out that some of the autism increasing are due to like-minded people getting together (especially those who are very left brained mathmatical type folks - myself and my wife). In the past you had fewer mates to choose from. These days people tend to gravitate towards someone similar. I would suspect that this would increase the rate of human evolution (at least w/respect to certain traits). Again many dead ends, but evolution only needs a few to pan out.