Avastin failed in 3rd line MBC.
Avastin has failed in 3rd line CRC as well.
Avastin has shown activity in MBC, NSCLC, RCC, pancreatic cancer, MDS, NHL
Avastin succeeded with flying colors in 1st line CRC
Is it unreasonable to believe that Avastin will pass the muster in 1st line MBC?
we are now speaking semantics, but if the potential market for a new indication is over 250 million, I consider that pipeline material.