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sam1933

09/28/08 3:04 AM

#79488 RE: ann441j #79482

Products & Services

Seems to still be breathing?



FOR THE FORENSICS MARKET



* DNAWitness TM 2.5 -
- Tests crime scene DNA to assist detectives, forensic scientists and medical examiners in corroborating eyewitness reports and confirming suspect identities. DNAWitness 2.5 provides a BioGeographical Ancestry report that includes a photo database for reference samples of individuals. Reported ancestral origins are Sub-Saharan African, Native American, East Asian and Indo-European.

* EuroWitness TM 1.0 -
- Tests crime scene DNA to determine more specific geographic origins if the test sample ancestry is 50% or more Indo-European. EuroWitness TM 1.0 provides a BioGeographical Ancestry report that includes relative percentages of Northern European, Southeastern European, Middle Eastern or South Asian.

* Retinome TM -
- A predictive test for individual eye color from DNA. RETINOME predicts eye color if the sample is 50% or greater European ancestry as to whether eye color is blue, mostly blue, brown or mostly brown. A representative eye photo database is also provided along with relevant photo database pictures of the individual references.

* STR-Witness TM -
- A genetic "matching" used as a bar code to track and report the samples. STR-Witness is the same test used for determining an individual's identity from an available DNA sample. Crime labs run this test to screen the Federal Bureau of Investigation's Combined DNA Index System, or CODIS, database for possible matches.

* DNAWitness-Y TM -
- A Y-chromosome test that determines the direct paternal ancestral lineage from the male sex chromosome. DNAWitness-Y TM can be used as an identification tool in cases where a mixture of male and female samples exists.

* DNAWitness-Mito TM --

A mitochondrial DNA test that examines ancestral lineages along the maternal line. DNAWitness-Mito TM can be used as an identification tool when other DNA testing fails to yield results or the DNA sample is too deteriorated.





PRODUCTS FOR THE CONSUMER PRODUCT MARKET
* AncestryByDNA
|DNAPrint® Genomics offers a unique and economical process for families to genetically verify their ancestral origins. Continue on to explore your family’s hereditary links to the past.


* EurasianDNA 1.0
product is similar except it measures European sub-ancestry. “European” ancestry from Ancestrybydna 2.5 actually refers to a type of ancestry shared by people who derived from the fertile crescent of the Middle East some 50,000 years ago and spread to occupy Europe, the Middle East, parts of Eurasia and South Asia. EurasianDNA 1.0 breaks the European ancestry into 4 groups, reporting individuals’ percentages for each: Northwestern European, Southeastern European, Middle Eastern and South Asian.

* EuropeanDNA 2.0,
our powerful new product which was launched in June 2007, further elucidates European sub-ancestry using 1,349 European Ancestry Informative Markers (SNP AIMs).

* Ancestry-Mito -
(Trace maternal heritage from mother's and grandmother's lineage and receive your maternal mitochondrial haplogroup)
* Ancestry-Y -
(Trace paternal heritage from father's and grandfather's lineage and receive your Y chromosome haplogroup MALE ONLY TEST)

*Amber Stick Version 2 -
- Fully Portable Storage Device Now Can Accommodate Electronic DNAPrint Sequence and Identifying Information for All Family Members, Including Pets
According to Craig Conway, National Director of Sales for Amber Stick, this is the most

* DNA Storage
comprehensive family information storage system on the market today.
The process to store your DNA is simple and painless. We will send you a DNA storage kit. That includes:
1) A sterile foam swab
2) An FTA Elute card



* STRMAP analysis
- is processed on ABI 3700 and 3100 equipment, state of the art analyzers that measure the Short Tandem Repeat (STR) units of DNA. This service offers the testing of the sex marker plus 15 STR locations of your DNA. These locations have been standardized over the past decade to serve as “DNA barcodes” for human identification and first generation relationships. Each individual has their information at these STR locations. The FBI uses 13 of these loci in its CODIS panel which is the standard used currently by most law enforcement agencies.


* Doggie DNAPrint® 1.0 Kit -
-a DNA-based test that looks at 204 unique canine Ancestry Informative Markers (CanAIMs) on the dog genome. This simple and painless test (only requires a cheek swab of your dog) harnesses the power of modern molecular biology and genomics technology to uncover your canine's genealogy.
Doggie DNAPrint® 1.0.0 beta database updated to 1.0.1 beta. 49 mixed breeds added.



OUR GENOTYPING SERVICES

* We provide services that range from sequencing and genotyping to the entire process of SNP discovery to large industrial customers. Contract genotyping is the process of reading a genetic sequence and identifying differences in the sequence letters. For example, in comparing diseased tissue with normal tissue, we are able to see the differences in the sequence letters. This information helps researchers understand how human differences are expressed at the gene level. They can then search for and develop preventative treatment and effective therapeutic courses to alleviate disease symptoms.


OUR PHARMACOGENOMICS PRODUCTS

THERANOSTICS

* PT-401 Anemia - Renal Failure
* PT-501 ADHD
* PT-502 Drug Addiction
* PT-503 Depression

DIAGNOSTIC

* OVANOME Ovarian Cancer
* STATINOME Safety of Statins
* PONV Post-Operative Nausea and Vomiting

Trademarks

* We regard our trademarks, copyrights, domain names, trade dress, trade secrets, proprietary technologies, and similar intellectual property as important to our success, and we rely on trademark, and copyright law, trade-secret protection, and confidentiality and/or license agreements with our employees, customers, partners, and others to protect our proprietary rights. We have licensed in the past, and expect that we may license in the future, certain proprietary rights, technologies or copyrighted materials, from third parties, and we rely on those third parties to defend their proprietary rights, copyrights and technologies.

We have registered the trademark for DNAPrint and claim common law trademark rights to the marks DNAWitness, EuroDNA and AncestryByDNA.



Patent Applications
Efficient Methods and Apparatus for High-Throughput Processing of Gene Sequence Data.

US 7,110,885 (granted)

Methods fo the Identification of Genetic

US 7,107,155 (granted)

Features for Complex Genetics Classifiers

PCT/US02/38326

Methods for the Identification of Genetic.

US 7,107,155 (granted)

CA 2,468,961

EP 02794095.6

JP549497/2003

AU2002359549

Methods and Apparatus for use in Genetics Classification Including Classification Tree

US10/496,226

Analysis

PCT/USO2/38309

CA2,498,570

EP02789948.3

JP550120/2003

AU2002352985

Methods and Apparatus for use in Complex Genetics Classification

US10/495,962

Based on Correspondence Analysis and Linear-Quadratic Analysis

PCT/US02/41465

CA2,468,601

EP02789948.3

JP549549/2003

AU2002361871

Composition and Methods for the Inference

US11/397,454

Of Pigmentation Traits

PCT/US02/16789

AU2002/312112

CA2,448,569

EP02739467.5

hk04109585.8

JP2003/500216

Compositions and Methods for Inferring

US10/188,359

A Response to a Statin

PCT/US02/20847

AU2002/316485

CA2,486,789

EP02746794.3

JP2003/509083

Single Nucleotide Polymorphisms and Combinations Thereof Predictive of

PCT/US02/38345

Paclitaxel Responsiveness in Cancer Patients

AU2002360452

CA2,468,312

EP02795709.1


HK05102575.4

JP2003-546736

US10/496,605

Compositions and Methods for Inferring Ancestry

US10/644,594

PCT/US03/26229

AU2003265572

CA2,496,155

EP03788685.0

JP2005-502072

Methylphenidate Analogs and Methods of Use Thereof

US11/256063

PCT/US2005/038030


Multiplex Assays for Inferring Ancestry

331832-000045/WO

Compositions and Methods for Inferring an Adverse Effect in Response to a Drug . . . .

US05/41326

Methods and Compositions for Inferring Eye Color

US10/589,291

PCTUS05/04513

EP05723003.9

Modified Polypeptides with Increased Biological Activity

US 5,580,853 (Granted)

US 5,747,445 (Granted)

PCT/US97/22503

JP PCT 10524930

US 5,919,758 (Granted)

US 6,107,272 (Granted)


PCT/US95/03242

EPO 0 751 959

Integrated disease information system

US 6,108,635 (granted)

Hierarchical Biological Modeling System and Method as

US 5,808,918 (granted)

Restricted to three of five original claims upon re-examination

At the USPTO in 2001

DNA polymorphism associated with Crohn’s Disease

PCT WO 01/042511

US 239403

IBD candidate gene

US 60/362,700

US 60/362,717

US 60/342,388

US 10/327,189

PCT/IB02/05560

JP 2003-554727

EU 02781695.8

AU 2002348745

PCT/IB2002/005560


SYSTEMS AND METHODS FOR IDENTIFYING AND TRACKING INDIVIDUALS

(WO/2008/005309)

PCT/US2007/015088





I will send you the sources for free

sam