With the longstanding amyloid dogma on shakier ground, the field is not going to cast all its hopes with a single replacement. The TauRx thing is pretty much out of the blue (methylene blue to be exact) for everybody, but I have followed Allon Therapeutics closely for years. I think more attention is going to be paid to downstream approaches that do not require the precise identification of the upstream cause, and neurotrophic upregulation via Ampakines, or other means, will get more resources because of that.
NeuroInvestment