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keitern

04/07/08 9:28 AM

#9777 RE: MTB #9776

MTB, I read the post with great interest several times. Rather than read multiple posts on the effects of a R/S I thought I would ask for some corraboration on your thoughts which are beyond my abilities to fully understand. I admire your critical thinking abilities.

As far as what I think about your post, I wish I could better understand the following:

2)ATIII has beneficial antiflammatory properties. The heparin-binding sites on ATIII also bind the HSPG's (think of them as molecular fingers sticking out from a number of cells, including white blood cells and cells lining the blood vessels) and in doing so, DECREASE the release of inflammatory mediators. It is THIS function that appears to be completely disabled by even very small amounts of therapeutically-administered heparin, as the 'therapeutic' heparin administered in the blood appears to prevent ATIII's binding to the HSPG's on cells in the body.

but I havn't the proper background. However, I am interested in the "beneficial antiflammatory properties". If the affected area becomes inflamed, swells, constricts blood flow, causes pain, causes more problems......and so on, then antiflammatory properties of Atryn would seem to be a wonderful enhancement.