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apljack

02/16/08 7:12 PM

#1173 RE: Bio_pete #1171

"I really don't see it used except for acute pain indications due to its short duration. It only works for 15 - 30 minutes until you have to take another hit."

But the fast acting onset of intranasal delivery might be attractive to patients with these conditions, particularly when a strategic intervention might abort an otherwise serious pain event (ie eg coughing that exacerbates headache or sore throat pain, or prodromal migraine headache.)

What I know from my clinical practice is that pain meds that are approved and on the market are tried in a variety of off-label ways for a variety of pain conditions. Particularly notable are the chronic migraine patients who usually play the "pain management" game and settle on the med. or med. regimen that they've accepted as best for their personal response.

JM2C

aj