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p3analyze

02/15/08 1:48 PM

#5382 RE: rancherho #5381

Three questions:
1.Was the correlation between antibody response and OS adjusted for baseline prognostic covariates?
2. Was antibody response measured during the same timeframe for all subjects and when?

3. Are the two antigens FLJ14668 and HLA-A24 specific to prostate cancer?

Thanks!
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rungsatsz

02/15/08 2:18 PM

#5383 RE: rancherho #5381

OT_

Rancherho,

Enjoy your commentary hereon. What Company were you in at the Boat School?

DNDN long since 2/05.

Rungsatsz '68
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iwfal

02/15/08 3:57 PM

#5385 RE: rancherho #5381

This is strong scientific validation for GVAX Phase 2 results.

This is wildly incorrect. To my knowledge **ALL** active immunotherapies show a strong correlation between some measure of immune responsiveness to vaccine and survival. Then the phase iii results come in a dud.

Seriously, find my an active immunotherapy that DIDN'T at some point tout exactly this kind of immune responsiveness. And all have failed to date.

Clark